If you choose one amino acid as part of your daily supplement, L-Glutamine would definitely be a great choice. Because glutamine makes up about 60 percent of the amino acids in skeletal muscle, it is not surprising that intramuscular glutamine regulation has a significant effect on skeletal muscle metabolism. And, glutamine actually helps you store muscle glycogen, a major fuel source for intense exercise.
To make glutamine more attractive, the main benefits of L-Glutamine are:
o Muscle prevention and support in fat loss (from increased muscle and increased production of human growth hormone)
o support of enterocytes (intestinal lining cells) in which all nutrients are absorbed
o Improved or improved immune system
o Better mental clarity and muscle contraction as it is the amino acid found in the highest concentrations of spinal and cerebral fluid.
Read on for more detailed and biochemical explanations.
So, what is L-Glutamine?
L-Glutamine is the most "free" amino acid in the body, but it is considered an "essential amino acid" because it can be synthesized in the body from glutamate by the enzyme "glutamine synthetase" or by oxidation of proline in the liver. However, scientists have classified glutamine as a "necessary" amino acid, because under certain conditions (such as severe stress), glutamine may be needed in higher quantities, and glutamine is found in higher concentrations than amino acids. others in vital tissues include the brain, intestinal mucosa cells, immune cells, and skeletal and smooth muscle.
Technically, Glutamine acts as a nitrogen bridge by absorbing and releasing nitrogen around the body. Nitrogen is an essential component of DNA (a living genetic material) and is essential for muscle building. Glutamine also converts to alpha-ketoglutarate, an essential nutrient for energy production in the Krebs cycle. Of particular interest is the growing evidence that glutamine plays an important role in skeletal muscle maintenance, gastrointestinal function, immune health, brain function and recovery from physical stress. Due to L-glutamine deficiency associated with physical stress, supplements have proven to be very beneficial. These amino acids are easily absorbed from the intestinal tract, and have a slight sweetness, making the supplement easy and fun.
Glutamine and Skeletal Muscles
In muscles, the concentration of free glutamine appears to affect whether the muscle will break (low glutamine content) or build up (high glutamine content). Athletes suffering from chronic fatigue have shown a prolonged decline in blood glutamine concentration. This reduced concentration may impede immune health and lead to slower recovery times due to exercise and physical stress. Subjects who supplemented oral glutamine showed high plasma concentrations of both glutamine and growth hormone, suggesting potential benefits of glutamine in terms of body composition.
The Benefits of L-Glutamine
Glutamine is also a major contributor to proper bowel function. By serving as a source of energy for highly active cells, many studies have shown the important role of glutamine as a key fuel for intestinal epithelium and its key role in maintaining gut structure and function in stress-related situations. People diagnosed with large bowel syndrome (IBS, Crohn's, etc.) have also reported good effects with increasing L-Glutamine. Glutamine deficiency also results in impairment of the immune system and / or gastrointestinal system.
Patients recovering from heavy physical activity have an increased demand for glutamine which may be due to increased use of the immune system and decreased integrity of trauma tissue. Due to the physical demands of stress, amino acids are essential to the healing process. Glutamine has proven to be important right now as demand may exceed that available from muscle stores. A recent study at the Geisinger Medical Center noted that increased muscle damage following extreme physical activity was partly due to glutamine deficiency. From their observations, the researchers concluded that glutamine supplementation would prevent muscle damage and improve the healing process. Finally, there is evidence that glutamine is useful for alcohol addiction. In one preliminary study, alcohol consumption increased slightly when 1,000mg of glutamine was administered orally.
Support for Immune Health
It is understood that immune health depends on macrophages and lymphocytes (a type of white blood cell). Macrophages play important roles in immune responses and exhibit anti-bacterial and anti-tumor activity by presenting strong compounds such as hydrogen peroxide, superoxide and lysozyme enzymes, while lymphocytes stabilize immune status through activation of B and T cells, leading to increased glutamine use.
For this purpose, glutamine levels are very high in white blood cells; appears to be essential to normal defense function; and is essential for RNA & DNA synthesis of lymphocytes. In experimental cell culture, lymphocytes are less effective when glutamine is reduced. When glutamine was added to the culture medium, lymphocyte proliferation increased significantly to normal levels. Further studies show that lowering glutamine concentration decreases adequate immune health, emphasizing the importance of supplements for individuals whose immune status is emphasized by heavy physical activity.
Support for Neurological Health
Because glutamine is one of the most abundant amino acids in cerebrospinal fluid, it easily enters the brain where it can serve as a precursor to the neurotransmitter's gamma-aminobutyric acid (GABA). GABA and serotonin are important neurotransmitters with many functions including increased well-being and tranquility. In a study conducted at St. John's Hospital Joseph's Church in Phoenix, researchers show that glutamine supplementation helps maintain amino acid concentration in brain tissue, increases tryptophan intake and increases serotonin synthesis.
Safety & Side Effects
More and more research is continuing to show significant results with L-Glutamine supplementation with no adverse side effects of up to 60g per day for intensive training athletes.
Recommended dose
L-Glutamine is recommended for athletes with intense training, which is subject to immune toxins or weak immune systems, and postoperative and bowel syndrome (IBS) patients. Normal doses range from 2g a day to 60g a day. The optimal dose is 5-10 days in divided doses. This is a perfect addition to the cold and winter and all year round. To release increased GH, take 10g L-Glutamine when waking up on an empty stomach, and before bed. It is also highly recommended to have pre and post workout exercises.
With all the benefits glutamine has to offer, and available at a much cheaper price, it only makes sense to make this your main supplement. Now you can build your immune system and improve your physical performance, all in one super supplement.
The Preferred Fuel Source: L-Glutamine
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